![]() These illnesses, some of which are highly heritable, are currently classified across several DSM-IV-TR diagnostic categories. ![]() Pathological impulsivity and compulsivity characterize a broad range of mental disorders and are the core and most debilitating symptoms, at least phenotypically, in some of the disorders in which these behaviors occur. Understanding these brain mechanisms may lead to targeted treatment strategies for these symptom domains when impulsivity and compulsivity become dysfunctional. Impulsivity and compulsivity are natural behaviors controlled by brain mechanisms that are essential for survival in all species. Dr Berlin reports no conflicts of interest concerning the subject matter of this article Dr Hollander reports that he has received research grants from Solvay, Abbott, Ortho-McNeil, and Somaxon. Dr Berlin is assistant professor and Dr Hollander is Esther and Joseph Klingenstein Professor and chair, department of psychiatry at Mount Sinai School of Medicine in New York Dr Hollander is also director of the Seaver and New York Autism Center of Excellence at Mount Sinai. To determine whether this article meets the continuing education requirements of your specialty, please contact your state licensing board. Continuing medical education credit is available for most specialists. Who will benefit from reading this article? Psychiatrists, primary care physicians, neurologists, nurse practitioners, and other health care professionals.
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